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Stem cell transplant is often used to treat children with leukaemia, but the pre-transplant treatment used to replace bone marrow can have side-effects. This project is pioneering a way of using specially designed antibodies to create space for donor stem cells. If successful, this approach should make it possible to carry out transplants in a much safer way.
Our funding is helping to develop new approaches to stem cell transplant, which is often used to treat children with leukaemia. The aim is to pioneer the use of specially designed antibodies to create space for donor stem cells.
This research project on stem cell transplant has been successfully completed. Your donations allow us to fund ground-breaking research that can improve treatments given to children with cancer. Thank you. Your help allows us to continue to find ways to drive up the chances of survival for children with cancer and reduce the toxic side effects that can affect the rest of their lives.
Development of an anti c-kit antibody to improve outcomes after stem cell transplantation for acute myeloid leukaemia
Professor Persis Amrolia
UCL Institute of Child Health
London, WC1N 1EH
12 June 2014
3 years
£267,162
Childhood cancer immunotherapy using blood cells from umbilical cord blood
Related research – Professor Waseem QasimImmunotherapy is an important new approach in the treatment of cancer. In this project, Professor Waseem is pioneering an
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